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Anti-CTLA4 (ipilimumab biosimilar) mAb

Product Overview
Common Name BMS-734016, MDX-010, MDX-CTLA-4
Buffer Preservative: 0.1% Procline 300
Constituents: 50% Glycerol; PBS, pH 7.4; 0.1% BSA
Guarantee 12 months from date of dispatch
Catalog Number BME100022
Package 50 μl $80.00 ; 100 μl $160.00
Synonyms CTLA4, CD152
Host Species Homo sapiens
IgG type IgG1
Clonality Monoclonal
Formulation Liquid
Purification Purified from cell culture supernatant by affinity chromatography
Reactivity Human
Applications ELISA
Recommended Dilutions ELISA 1:5000-10000
Storage Store at -20°C (Avoid repeated freezing and thawing)
Usage Research use only
Images

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Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human CTLA4, mFc-His tagged protein (PME100017) can bind Anti-CTLA4 Neutralizing antibody in a linear range of 0.13-16.0 ng/ml.


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Figure 2. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human CTLA4, hFc tagged protein (PME100479) can bind Anti-CTLA4 Neutralizing antibody in a linear range of 0.64-80.0 ng/ml.

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Figure 3. HEK293 cell line transfected with irrelevant protein (B) and human CTLA4 (A) were surface stained with anti-CTLA4 neutralizing antibody 1μg/ml (ipilimumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.


Background Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals.
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