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Human CEACAM5 Protein, His Tag

产品概述
Catalog Number PME100071
Package 10 μg ¥600.00 ; 50 μg ¥2350.00 ; 100 μg ¥3380.00
Description Recombinant human CEACAM5 protein with C-terminal 6×His tag
Synonyms CEACAM-5,CD66e,CEA,Meconium antigen 100
Uniprot ID P06731
Expression Host HEK293
Tag C-6×His tag
Molecular Characterization 这里上传图片
Molecular Weight The protein has a predicted molecular mass of 72.2 kDa after removal of the signal peptide. The apparent molecular mass of CEACAM5-His is approximately 100-130 kDa due to glycosylation.
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Storage Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage Research use only
Images

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Figure 1. Human CEACAM5 Protein, His Tag on SDS-PAGE under reducing condition.

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Figure 2. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human CEACAM5, His tagged protein (PME100071) can bind Anti-CEACAM5 Antibody (BME100035) in a linear range of 2.56-320 ng/ml.

Background This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants.
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