Home>目录产品>生物活性蛋白

Sales Promotion Get free trial
Contact Us Phone:+86-18062749453 Email:info@dimabio.com
Please leave your suggestion or opinion, we will reply you as soon as possible, thank you!×

Human CD27 Protein, hFc Tag

Product Overview
Catalog Number PME100475
Package 10 μg $60.00 ; 50 μg $235.00 ; 100 μg $338.00
Description Recombinant human CD27 protein with C-terminal human Fc tag
Synonyms CD27, TNFRSF7, S152, T14, Tp55
Uniprot ID P26842
Expression Host HEK293
Tag C-Human Fc
Molecular Characterization 这里上传图片
Molecular Weight The protein has a predicted molecular mass of 45.3 kDa after removal of the signal peptide.The apparent molecular mass of CD27-hFC is approximately 55-70 kDa due to glycosylation.
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Storage Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage Research use only
Images

这里上传图片

Figure 1. Human CD27 Protein, hFc Tag on SDS-PAGE under reducing condition.

这里上传图片

Figure 2. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human CD27, hFc tagged protein (PME100475) can bind Anti-CD27 Neutralizing antibody (BME100018) in a linear range of 3.2-80.0 ng/ml.

这里上传图片

Figure 3. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human CD27, hFc tagged protein (PME100475) can bind Human CD70,mFc-His tagged protein (PME100042) in a linear range of 3.2-400 ng/ml.

Background The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Data Download
Datasheet Download COA Download
MSDS Download
Please leave your mobile phone number, and we will contact you as soon as possible. Thank you!×

Phone+86-027-87002742

Address Room 411-6, Building 2, No. 8, Jinfeng Road, High tech Zone, Suzhou

Emailinfo@dimabio.com

Websitewww.dimabio.com

Follow Us On