Home>目录产品>生物活性蛋白

Sales Promotion Get free trial
Contact Us Phone:+86-18062749453 Email:info@dimabio.com
Please leave your suggestion or opinion, we will reply you as soon as possible, thank you!×

Human IL6R Protein, His Tag

Product Overview
Catalog Number PME100109
Package 10 μg $60.00 ; 50 μg $245.00 ; 100 μg $358.00
Description Recombinant Human IL6R Protein with C-terminal 6×His tag
Synonyms CD126; gp80; IL-6R-1; IL-6RA; IL6Q; IL6RA; IL6RQ
Uniprot ID P08887
Expression Host HEK293
Tag C-6×His tag
Molecular Characterization 这里上传图片
Molecular Weight The protein has a predicted molecular mass of 39.4 kDa after removal of the signal peptide.The apparent molecular mass of IL6R-His is approximately 55-70 kDa due to glycosylation.
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Storage Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage Research use only
Images

这里上传图片

Figure 1. Human IL6R Protein, His Tag on SDS-PAGE under reducing condition.

这里上传图片

Figure 2. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human IL6R, His tagged protein (PME100109) can bind Human IL6, mFc-His tagged protein (PME100032) in a linear range of 0.512-40000 ng/ml.

这里上传图片

Figure 3. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human IL6R, His tagged protein (PME100109) can bind Anti-IL6R Neutralizing antibody (BME100041) in a linear range of 0.64-80 ng/ml.

Background This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.
Data Download
Datasheet Download COA Download
MSDS Download
Please leave your mobile phone number, and we will contact you as soon as possible. Thank you!×

Phone+86-027-87002742

Address Room 411-6, Building 2, No. 8, Jinfeng Road, High tech Zone, Suzhou

Emailinfo@dimabio.com

Websitewww.dimabio.com

Follow Us On