Human CD123 Protein, hFc-His Tag
| Catalog Number | PME100003 |
|---|---|
| Package | 10 μg $60.00 ; 50 μg $245.00 ; 100 μg $358.00 |
| Description | Recombinant human CD123 protein with C-terminal human Fc and 6×His tag |
| Synonyms | IL3R, IL3RA, IL-3Ra, IL-3R-alpha, IL3RAY, IL3RX, IL3RY, CD123 antigen, CD123, hIL3Ra, hIL-3Ra, MGC34174, IL-3 R alpha |
| Uniprot ID | P26951 |
| Expression Host | HEK293 |
| Tag | C-Human Fc and 6×His tag |
| Molecular Characterization |
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| Molecular Weight | The protein has a predicted molecular mass of 80-90 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Storage | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage | Research use only |
| Images |
Figure 1. Human CD123, hFc-His Tag on SDS-PAGE under reducing condition.
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| Background | Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells. |
| Datasheet | Download | COA | Download |
|---|---|---|---|
| MSDS | Download | ||
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