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Anti-DNMT3A, Rabbit pAb

Product Overview
Clone IDDM8
ImmunogenRecombinant human SIRPα (Glu31-Arg370) produced by using human HEK293 cells
Predicted Molecular Weight66.9 kDa
Catalog Number DME200013
Package
Synonyms TBRS; DNMT3A2; M.HsaIIIA
Host Species Rabbit
IgG type IgG
Clonality Rabbit polyclonal
Formulation Liquid
Purification Antigen affinity purification
Reactivity Human, Mouse, Rat
Applications ELISA, WB, IHC
Recommended Dilutions ELISA 5000-10000; WB 200-1000; IHC 50-200
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Usage Research use only
Images

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The image1 is immunohistochemistry of paraffin-embedded Human tonsil tissue using DME200013(DNMT3A Antibody) at dilution 1/80, the image2 is treated with fusion protein. (Original magnification: ×200)

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The image3 is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using DME200013(DNMT3A Antibody) at dilution 1/80, the image4 is treated with fusion protein. (Original magnification: ×200)

The image5: Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Hela and 231 cell lysates, Primary antibody: DME200013(DNMT3A Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 2 minutes

Background CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
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