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Anti-IL6, Rabbit pAb

Product Overview
Clone IDDM8
ImmunogenRecombinant human SIRPα (Glu31-Arg370) produced by using human HEK293 cells
Predicted Molecular Weight66.9 kDa
Catalog Number DME200016
Package
Synonyms HGF; HSF; BSF2; IL-6; IFNB2
Host Species Rabbit
IgG type IgG
Clonality Rabbit polyclonal
Formulation Liquid
Purification Antigen affinity purification
Reactivity Human
Applications ELISA, IHC
Recommended Dilutions ELISA 5000-10000; IHC 25-100
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Usage Research use only
Images

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The image1 is immunohistochemistry of paraffin-embedded Human breast cancer tissue using DME200016(IL6 Antibody) at dilution 1/20, the image2 is treated with fusion protein. (Original magnification: ×200)

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The image3 is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using DME200016(IL6 Antibody) at dilution 1/20, the image4 is treated with fusion protein. (Original magnification: ×200)

Background This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis.
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