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Anti-KIT, Rabbit pAb

Product Overview
Clone IDDM8
ImmunogenRecombinant human SIRPα (Glu31-Arg370) produced by using human HEK293 cells
Predicted Molecular Weight66.9 kDa
Catalog Number DME200017
Package
Synonyms PBT; SCFR; C-Kit; CD117
Host Species Rabbit
IgG type IgG
Clonality Rabbit polyclonal
Formulation Liquid
Purification Antigen affinity purification
Reactivity Human
Applications ELISA, IHC
Recommended Dilutions ELISA 2000-5000;IHC 25-100
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Usage Research use only
Images


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The image1 is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using DME200017(KIT Antibody) at dilution 1/25, the image2 is treated with synthetic peptide. (Original magnification: ×200)

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The image3 is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using DME200017(KIT Antibody) at dilution 1/25, the image4 is treated with synthetic peptide. (Original magnification: ×200)


Background This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.
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