Anti-SLAMF1, Rabbit pAb
Clone ID | DM8 |
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Immunogen | Recombinant human SIRPα (Glu31-Arg370) produced by using human HEK293 cells |
Predicted Molecular Weight | 66.9 kDa |
Catalog Number | DME200019 |
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Package | |
Synonyms | SLAM; CD150; CDw150 |
Host Species | Rabbit |
IgG type | IgG |
Clonality | Rabbit polyclonal |
Formulation | Liquid |
Purification | Antigen affinity purification |
Reactivity | Human |
Applications | ELISA, WB |
Recommended Dilutions | WB 200-1000; ELISA 1000-2000 |
Storage | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Usage | Research use only |
Images |
Gel: 8%SDS-PAGE, Lysate: 50 μg, Lane: Jurkat cells, Primary antibody: DME200019(SLAMF1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute |
Background | High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates. |
Datasheet | Download | COA | Download |
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MSDS | Download |