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Anti-SLAMF1, Rabbit pAb

Product Overview
Clone IDDM8
ImmunogenRecombinant human SIRPα (Glu31-Arg370) produced by using human HEK293 cells
Predicted Molecular Weight66.9 kDa
Catalog Number DME200019
Package
Synonyms SLAM; CD150; CDw150
Host Species Rabbit
IgG type IgG
Clonality Rabbit polyclonal
Formulation Liquid
Purification Antigen affinity purification
Reactivity Human
Applications ELISA, WB
Recommended Dilutions WB 200-1000; ELISA 1000-2000
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Usage Research use only
Images

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Gel: 8%SDS-PAGE, Lysate: 50 μg, Lane: Jurkat cells, Primary antibody: DME200019(SLAMF1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute

Background High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
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