| Target | |
|---|---|
| Synonyms | Butyrophilin protein |
| Description | Recombinant Cynomolgus BTN3A1 protein with C-terminal 6×His tag |
| Delivery | In Stock |
| Uniprot ID | A0A330KVC6 |
| Expression Host | HEK293 |
| Tag | C-6×His Tag |
| Molecular Characterization | BTN3A1(Gln1-Ser218) 6×His tag |
| Molecular Weight | The protein has a predicted molecular mass of 24.3 kDa after removal of the signal peptide. The apparent molecular mass of cBTN3A1-His is approximately 25-35 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Butyrophilin subfamily 3 member A1 (BTN3A1) is also known as CD277 and BTF5, which belongs to the immunoglobulin superfamily and contains one B30.2/SPRY domain and two Ig-like V-type (immunoglobulin-like) domains. BTN3A1 plays a role in T-cell activation and in the adaptive immune response. Also, BTN3A1 regulates the proliferation of activated T-cells and the release of cytokines and IFNG by activated T-cells. Furthermore, BTN3A1 mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate. |
| Usage | Research use only |
Cynomolgus BTN3A1 Protein, His Tag
Price:10μg $120.00; 50μg $380.00; 100μg $570.00
Product Data
Images
Figure 1. Cynomolgus BTN3A1 Protein, His Tag on SDS-PAGE under reducing condition.