| Target | |
|---|---|
| Synonyms | CRISTIN1;PWTSR;THSD2 |
| Description | Recombinant human RSPO3(22-146) protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | Q9BXY4 |
| Expression Host | HEK293 |
| Tag | C-Human Fc Tag |
| Molecular Characterization | RSPO3(22-146)(Ser19-Glu351) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 38.6 kDa after removal of the signal peptide. The apparent molecular mass of RSPO3(22-146)-hFc is approximately 35-55 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture. This gene may be involved in tumor development. [provided by RefSeq, Jul 2013] |
| Usage | Research use only |
Human RSPO3 (22-146) Protein, hFc Tag
Price: 10μg $72.00; 50μg $274.00 ; 100 μg $411.00
Product Data
Images
Figure 1. Human RSPO3(22-146) Protein, hFc Tag on SDS-PAGE under reducing condition.