| Target | |
|---|---|
| Synonyms | TNFRSF12A;FGF-inducible 14;FN14;TweakR;CD266 |
| Description | Recombinant human TweakR protein with C-terminal mouse Fc tag |
| Delivery | In Stock |
| Uniprot ID | Q9NP84 |
| Expression Host | HEK293 |
| Tag | C-Mouse Fc Tag |
| Molecular Characterization | TweakR(Glu28-Pro80) mFc(Pro99-Lys330) |
| Molecular Weight | The protein has a predicted molecular mass of 31.8 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 90% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | TNFRSF12A (TNF Receptor Superfamily Member 12A) is a Protein Coding gene. Diseases associated with TNFRSF12A include Multiple Sclerosis and Stroke;Ischemic. Among its related pathways are ERK Signaling and CDK-mediated phosphorylation and removal of Cdc6 |
| Usage | Research use only |
Human TweakR Protein, mFc Tag
Price: 10μg $78.00; 50μg $310.00 ; 100 μg $460.00
Product Data
Images
Figure 1. Human TweakR Protein, mFc Tag on SDS-PAGE under non-reducing (NR) and reducing (R) conditions.
Figure 2. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human TweakR, mFc tagged protein (PME100463) can bind Anti-TweakR Neutralizing antibody (BME100031) in a linear range of 0.64-80 ng/ml.