Target | |
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Synonyms | Fibroblast growth factor 8; Androgen-induced growth factor; Heparin-binding growth factor 8; AIGF; HBGF-8; FGF-8B |
Description | Recombinant Human Fibroblast Growth Factor 8f is produced by our E.coli expression system and the target gene encoding Gln23-Arg244 is expressed with a 6His tag at the N-terminus. |
Delivery | In Stock |
Uniprot ID | P55075-4 |
Expression Host | E.coli expression system |
Tag | |
Molecular Characterization | #N/A |
Molecular Weight | 27.7 KDa |
Purity | Greater than 95% as determined by reducing SDS-PAGE. |
Formulation & Reconstitution | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
Storage & Shipping | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Usage | Research use only |
Background | Fibroblast growth factor 8 (FGF8) is a member of the fibroblast growth factor family. It is discovered as a growth factor essential for the androgen-dependent growth of mouse mammary carcinoma cells. Mouse FGF8b shares 100% aa identity with human FGF8b. FGF8 is widely expressed during embryogenesis, and mediates epithelial-mesenchymal transitions. It plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. It is required for normal brain, eye, ear, limb development during embryogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. |
Product Data
Images
Figure 1. Greater than 95% as determined by reducing SDS-PAGE.