| Target | |
|---|---|
| Synonyms | CHNG1; hTSHR-I; LGR3 |
| Description | Human TSHR full length protein-MNP |
| Delivery | In Stock |
| Uniprot ID | P16473 |
| Expression Host | HEK293 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Autoimmune thyroid disease, Neuroactive ligand-receptor interaction |
| Molecular Weight | The human full length TSHR protein has a MW of 86.8 kDa |
| Formulation & Reconstitution | Lyophilized from PBS (pH 7.4). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. |
| Usage | Research use only |
Human TSHR full length protein-MNP
Price: 50 μg $1200.00 ; 100 μg $1600.00
Product Data
Images
Figure1. Elisa plates were pre-coated with 0.5μg/per well purified human TSHR full length membrane nanoparticles. Serial diluted anti-TSHR monoclonal antibody (BME100080) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-TSHR monoclonal antibody binding with TSHR full length membrane nanoparticles is 111.6ng/ml.