| Target | |
|---|---|
| Synonyms | CD14 Molecule;Myeloid Cell-Specific Leucine-Rich Glycoprotein;CD14 Antigen;Monocyte Differentiation Antigen CD14 |
| Description | Recombinant Human CD14(20-352) Protein with C-terminal 7×His tag |
| Delivery | In Stock |
| Uniprot ID | P08571 |
| Expression Host | HEK293 |
| Tag | C-7×His Tag |
| Molecular Characterization | CD14(Thr20-Cys352) 7×His tag |
| Molecular Weight | The protein has a predicted molecular mass of 36.7 kDa after removal of the signal peptide. The apparent molecular mass of CD14(20-352)-7xHis is approximately 35-55 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2020] |
| Usage | Research use only |
Human CD14(20-352) Protein, His Tag
Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00
Product Data
Images
Figure 1.Human CD14(20-352) Protein, His Tag on SDS-PAGE under reducing condition.
Figure 2. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human CD14(20-352) Protein, His Tag (PME101230) can bind Anti-CD14(atibuclimab biosimilar) mAb (BME100205) in a linear range of 0.64–80 ng/mL.