DimAb® B cell seed libraries

What are DimAb® B cell libraries?

DimAb® B cell seed libraries are a pool of frozen B cells separated from positive immunized rabbits, which have been pre-validated by FACS as positive binders to the specific antigen proteins. Most of the libraries have also been used for the screening of lead mAbs molecules by our internal R&D team or customers. The molecules prepared from DimAb B cell libraries have shown diverse CDR sequences and good druggability in the downstream testing results. Each library should contain many potential binders for the drug discovery.

Key Features:

  • Pre-made B cell libraries containing diverse FACS binders for every target protein
  • Quick freezing in liquid nitrogen after PBMC isolation to prevent injury to the cells and keep the diversity of the original B cells.
  • Risk free, no binder no payment
  • Save your time for lead molecule discovery, skip the immunization and early screening steps (3~4 months).
  • Two steps validation:
    1. Polyclonal antibody validation of immunized rabbit serum as specific binders to the target proteins.
    2. Functionally validated to be capable to screen for FACS binder for lead mAbs molecules discovery.

DimAb® B cell seed libraries

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Contact us for your lead mAb molecules project!