| Common Name | BMS-734016, MDX-010, MDX-CTLA-4 |
|---|---|
| Synonyms | CTLA4;CD152 |
| Applications | ELISA; Flow Cyt |
| Recommended Dilutions | ELISA 1:5000-10000; Flow Cyt 1:100 |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Host Species | Homo sapiens |
| IgG type | IgG1 |
| Reactivity | Human |
| Target | |
| Uniprot ID | P16410 |
| Description | Anti-CTLA-4 (ipilimumab biosimilar) mAb |
| Delivery | In Stock |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals. |
| Usage | Research use only |
Anti-CTLA-4 (ipilimumab biosimilar) mAb
Price: 50μg $82.00 ; 100 μg $162.00
Product Data
Images
Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human CTLA4, mFc-His tagged protein (PME100017) can bind Anti-CTLA4 Neutralizing antibody in a linear range of 0.13-16.0 ng/ml.
Figure 2. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human CTLA4, hFc tagged protein (PME100479) can bind Anti-CTLA4 Neutralizing antibody in a linear range of 0.64-80.0 ng/ml. In order to specifically detect BME100022, mouse anti-human Fab-specific antibody was used as detection antibody.
Figure 3. HEK293 cell line transfected with irrelevant protein (B) and human CTLA4 (A) were surface stained with anti-CTLA4 neutralizing antibody 1μg/ml (ipilimumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.