| Target | |
|---|---|
| Synonyms | C-C Motif Chemokine 28;Mucosae-Associated Epithelial Chemokine;MEC;Protein CCK1;Small-Inducible Cytokine A28;CCL28;SCYA28 |
| Description | Recombinant Human C-C Motif Chemokine 28 is produced by our E.coli expression system and the target gene encoding Ser20-Tyr127 is expressed. |
| Delivery | In Stock |
| Uniprot ID | Q9NRJ3 |
| Expression Host | E.coli |
| Tag | |
| Molecular Characterization | Not available |
| Molecular Weight | 12.49 KDa |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Formulation & Reconstitution | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. CCR10 (GPR2 orphan receptor) is also the receptor for CCL27/CTACK. CCL28 is preferentially expressed by epithelial cells of diverse tissues, with highest expression level in normal and pathological colon. It is also expressed in normal and asthmatic lung tissues. Human and mouse CCL28 shares 83% sequence identity in their mature regions. |
| Usage | Research use only |
Human CCL28 Protein
Price: 50 μg $400.00
Product Data
Images
Figure 1. Greater than 95% as determined by reducing SDS-PAGE.