Target | |
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Synonyms | Interferon Gamma; IFN-Gamma; Immune Interferon; IFNG |
Description | Recombinant Human Interferon Gamma is produced by our Mammalian expression system and the target gene encoding Gln24-Gln166 is expressed. |
Delivery | In Stock |
Uniprot ID | P01579 |
Expression Host | HEK293 |
Tag | |
Molecular Characterization | #N/A |
Molecular Weight | 16.8 KDa |
Purity | Greater than 95% as determined by reducing SDS-PAGE. |
Formulation & Reconstitution | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 4% Mannitol, 2% Sucrose, 0.02% Tween80, pH7.4. |
Storage & Shipping | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Usage | Research use only |
Background | IFNγ is the major interferon produced by mitogenically or antigenically stimulated lymphocytes. It is structurally different from type I interferon and its major activity is immunoregulation. It has been implicated in the expression of class II histocompatibility antigens in cells that do not normally produce them, leading to autoimmune disease. Interferon gamma is produced mainly byT-cells and natural killer cells activated by antigens, mitogens, or alloantigens. It is produced by lymphocytes expressing the surface antigens CD4 and CD8. IFNγ synthesis is induced by IL-2, FGF-basic, and EGF. |
Product Data
Images
Figure 1. Greater than 95% as determined by reducing SDS-PAGE.