| Target | |
|---|---|
| Synonyms | Beta-Nerve Growth Factor; Beta-NGF; NGF; NGFB;β-NGF; pro-Beta NGF |
| Package | 10 μg $67.00 ; 50 μg $202.00 |
| Description | Recombinant Human pro-Nerve Growth Factor is produced by our E.coli expression system and the target gene encoding Glu19-Ala241 is expressed. |
| Delivery | In Stock |
| Uniprot ID | P01138 |
| Expression Host | E.coli expression system |
| Tag | |
| Molecular Characterization | #N/A |
| Molecular Weight | 25 KDa |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Formulation & Reconstitution | Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl,500mM NaCl,5%Trehalose,5%Mannitol,0.01%tween80,1mM EDTA,pH8.0. |
| Storage & Shipping | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| Usage | Research use only |
| Background | The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration. |
Human pro-Beta NGF Protein
Price: 10 μg $67.00 ; 50 μg $202.00
Product Data
Images
Figure 1. Greater than 95% as determined by reducing SDS-PAGE.