Human pro-Beta NGF Protein

Price: 50 μg $360.00

SKU: PME30059 Category: ECD Proteins

Target	pro-Beta
Synonyms	Beta-Nerve Growth Factor;Beta-NGF;NGF;NGFB;-NGF;pro-Beta NGF
Description	Recombinant Human pro-Nerve Growth Factor is produced by our E.coli expression system and the target gene encoding Glu19-Ala241 is expressed.
Delivery	In Stock
Uniprot ID	P01138
Expression Host	E.coli
Tag
Molecular Characterization	Not available
Molecular Weight	25 KDa
Purity	Greater than 95% as determined by reducing SDS-PAGE.
Formulation & Reconstitution	Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl,500mM NaCl,5%Trehalose,5%Mannitol,0.01%tween80,1mM EDTA,pH8.0.
Storage&Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration.
Usage	Research use only
Conjugate	Unconjugated

Figure 1. Greater than 95% as determined by reducing SDS-PAGE.