Synonyms | AGMX1; AT; ATK; BPK; IGHD3; IMD1; PSCTK1; XLA |
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Molecular Characterization | BTK(Met1-Ser659)+3×Flag tag |
Uniprot ID | Q06187 |
Description | Recombinant Human BTK Protein with C-terminal 3×Flag tag |
Expression Host | HEK293 |
Molecular Weight | The protein has a predicted molecular mass of 79.2 kDa after removal of the signal peptide. |
Delivery | In Stock |
Purity | The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized proteins are shipped at ambient temperature. |
Usage | Research use only |
Background | The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013] |
Human BTK Protein, Flag Tag
Price: 10μg $71.00 ; 50μg $259.00 ; 100μg $389.00
Product Data
Images
Figure 1. Human BTK Protein, Flag Tag on SDS-PAGE under reducing condition.