| Tag | C-Flag Tag |
|---|---|
| Target | |
| Synonyms | 5-HT4, 5-HT4R |
| Description | Human 5HT4R full length protein-synthetic nanodisc |
| Delivery | 6~8weeks |
| Uniprot ID | Q13639 |
| Expression Host | HEK293 |
| Protein Families | GPCR,Transmembrane,Druggable Genome, |
| Protein Pathways | GPCRDB Class A Rhodopsin-like,Monoamine GPCRs, |
| Molecular Weight | The human full length 5HT4R protein has a MW of 43.8kDa |
| Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010] |
| Usage | Research use only |
| Conjugate | Unconjugated |

