| Tag | C-Flag Tag |
|---|---|
| Expression Host | HEK293 |
| Target | |
| Synonyms | ALSPDC, CHAK, CHAK1, LTRPC7, LTrpC-7, TRP-PLIK |
| Description | Human TRPM7 full length protein-synthetic nanodisc |
| Uniprot ID | Q96QT4 |
| Protein Families | Ion Channels: Transient receptor potential |
| Protein Pathways | N/A |
| Molecular Weight | The human full length TRPM7 protein has a MW of 212.7kDa |
| Delivery | 6~8weeks |
| Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution |
| Sterility | Products are supplied non-sterile. For cell culture applications, dilute in appropriate medium and sterile-filter (0.22 µm) prior to use. |
| Storage&Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene belongs to the melastatin subfamily of transient receptor potential family of ion channels. The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. The encoded protein is involved in cytoskeletal organization, cell adhesion, cell migration and organogenesis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam. The gene may also be associated with defects of cardiac function. [provided by RefSeq, Aug 2017] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human TRPM7 full length protein-synthetic nanodisc
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