| Tag | N-His, C-Single Strep Tag |
|---|---|
| Expression Host | E. Coli Cell free system |
| Target | |
| Description | Human CCR4 full length protein-Detergent (E.Coli) |
| Synonyms | CC-CKR-4; CD194; ChemR13; CKR4; CMKBR4 |
| Uniprot ID | P51679 |
| Protein Families | GPCR |
| Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction |
| Molecular Weight | The human CCR4 full length protein has a MW of 43.5kDa |
| Delivery | 1 week |
| Formulation & Reconstitution | Liquid, 50mM HEPES, 150mM NaCl, 0.06M, 0.012%CHS, pH8.2 |
| Sterility | Products are supplied non-sterile. For cell culture applications, dilute in appropriate medium and sterile-filter (0.22 µm) prior to use. |
| Storage&Shipping | Store at -80℃, Ship on dry ice. |
| Purity | >80% |
| Background | The protein belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine – MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human CCR4 full length protein-Detergent (E.Coli)
Price: 20μg $1,483.00; 100μg $2,913.00
Product Data Dima FAQ
Images Dima FAQ
Figure 1. Elisa plates were pre-coated with N-His, C-Single Strep Tag CCR4-Detergent (0.5μg/per well). Serial diluted anti-CCR4 antibody (BME100086) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-CCR4 antibody binding with CCR4-Detergent is 2.651 ng/mL.
Figure 2. Human CCR4-Detergent,N-His, C-Single Strep Tag on SDS-PAGE.
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