| Tag | C-Flag&Avi Tag |
|---|---|
| Target | |
| Synonyms | CACNLG |
| Description | Biotinylated Human CACNG1 full length protein-synthetic nanodisc |
| Delivery | In Stock |
| Uniprot ID | Q06432 |
| Expression Host | HEK293 |
| Protein Families | Druggable Genome, Ion Channels: Other, Transmembrane |
| Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway |
| Molecular Weight | The human full length CACNG1 protein has a MW of 25.0 kDa |
| Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Sterility | Products are supplied non-sterile. For cell culture applications, dilute in appropriate medium and sterile-filter (0.22 µm) prior to use. |
| Storage&Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is part of skeletal muscle 1,4-dihydropyridine-sensitive calcium channels and is an integral membrane protein that plays a role in excitation-contraction coupling. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs). |
| Usage | Research use only |
| Conjugate | Biotinylated |
Biotinylated Human CACNG1 full length protein-synthetic nanodisc
Price: 10 μg $990.00 ; 50 μg $4840.00 ; 100 μg $8800.00
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Figure 1. On a streptavidin-coated plate (0.1 µg/well) immobilized with biotinylated Human CACNG1 full-length protein-synthetic nanodisc (FLP100616B, 1 µg/mL, 100 µL/well), the Anti-Flag Rabbit mAb showed linear binding in the range of 1.6-8 ng/mL. In order to specifically detect FLP100616B, HRP Conjugated Goat anti Rabbit was used as detection antibody.
Figure 2. Biotinylated Human CACNG1-Nanodisc, C-Flag&Avi Tag on SDS-PAGE
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