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Human FASLG Protein, hFc Tag

Product Overview
Catalog Number PME101045
Package 10 μg $60.00 ; 50 μg $235.00 ; 100 μg $338.00
Description Recombinant human FASLG protein with C-terminal human Fc tag
Synonyms ALPS1B, APT1LG1, APTL, CD95-L, CD95L, CD178, FASL, TNFSF6, TNLG1A
Delivery 4-6 weeks
Uniprot ID P48023
Expression Host HEK293
Tag C-Human Fc
Molecular Characterization 这里上传图片
Molecular Weight The protein has a predicted molecular mass of 45.21 kDa after removal of the signal peptide.
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Storage Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage Research use only
Images


Background This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014]
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