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Human TGFBR1 Protein, hFc Tag

Product Overview
Catalog Number PME100103
Package 10 μg $60.00 ; 50 μg $230.00 ; 100 μg $340.00
Description Recombinant human TGFBR1 Protein with N-terminal Human Fc tag
Synonyms AAT5, ACVRLK4, ALK-5, ALK5, ESS1, LDS1, LDS1A, LDS2A, MSSE, SKR4, tbetaR-I, TBR-i, TBRI, TGFR-1
Delivery In Stock
Uniprot ID P36897
Expression Host HEK293
Tag N-Human Fc tag
Molecular Characterization 这里上传图片
Molecular Weight The protein has a predicted molecular mass of 36.3 kDa after removal of the signal peptide.The apparent molecular mass of hFc-TGFBR1 is approximately 40-53 kDa due to glycosylation.
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Storage Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage Research use only


Figure 1. Human TGFBR1 Protein, hFc Tag on SDS-PAGE under reducing condition.

Background The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.
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