| Target | |
|---|---|
| Synonyms | CD86, B7-2, B70, CD28LG2, LAB72, MGC34413 |
| Host Species | Rabbit |
| IgG type | Rabbit IgG |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | ELISA, Flow Cyt |
| Recommended Dilutions | ELISA 1/5000-10000;Flow Cyt 1/100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Buffer | 1XPBS |
| Formulation & Reconstitution | Liquid |
| Delivery | In Stock |
| Usage | Research use only |
| Background | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. |
Anti-B7-2 antibody(DM86), Rabbit mAb
Price: 10μg $99.00 ; 100 μg $438.00 ; 500 μg $1314.00
Product Data
Images
Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human B7-2 protein, mFc-His tagged protein (PME100034) can bind Rabbit anti-B7-2 monoclonal antibody (clone: DM86) in a linear range of 1-100 ng/ml.
Figure 2. Expi 293 cell line transfected with irrelevant protein (A) and human B7-2 (B) were surface stained with Rabbit anti-B7-2 monoclonal antibody 1μg/ml (clone: DM86) followed by Alexa 488-conjugated anti-rabbit IgG secondary antibody.