Rabbit/Human Fc chimeric IgG1
ELISA, Flow Cyt
ELISA 1/5000-10000;Flow Cyt 1/100
Purified from cell culture supernatant by affinity chromatography
|Formulation & Reconstitution||
Research use only
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Anti-FCGR3A antibody(DMC219), IgG1 Chimeric mAb
Price: 10μg $99.00 ; 100 μg $438.00 ; 500 μg $1314.00
SKU: DMC100219 Category: DimAb monoclonal antibodies
Figure 1. Flow cytometry analysis with Anti-FCGR3A (DMC219) on Expi293 cells transfected with human FCGR3A (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).