Clone ID | DMC221 |
---|---|
Target | |
Synonyms | Interferon alpha:beta receptor 1;IFN-R-1;IFN-alpha:beta receptor 1;CRF2-1;Type I interferon receptor 1 |
Host Species | Rabbit |
Description | Anti-IFNAR1 antibody(DMC221); IgG1 Chimeric mAb |
Delivery | In Stock |
Uniprot ID | P17181 |
IgG type | Rabbit/Human Fc chimeric IgG1 |
Clonality | Monoclonal |
Reactivity | Human |
Applications | ELISA; Flow Cyt |
Recommended Dilutions | ELISA 1:5000-10000; Flow Cyt 1:100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases; which in turn phosphorylate several proteins; including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor. |
Usage | Research use only |
Anti-IFNAR1 antibody(DMC221); IgG1 Chimeric mAb
Price: 10μg $99.00 ; 100 μg $446.00 ; 500 μg $1340.00
Product Data
Images
Figure 1. Flow cytometry analysis with Anti-IFNAR1 (DMC221) on Expi293 cells transfected with human IFNAR1 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
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