Clone ID | DMC282 |
---|---|
Target | |
Synonyms | IL-11 R alpha;IL-11 RA;IL11RA;Interleukin-11 receptor subunit alpha;IL-11 receptor subunit alpha;IL-11R subunit alpha;IL-11R-alpha |
Host Species | Rabbit |
Description | Anti-IL11RA antibody(DMC282); IgG1 Chimeric mAb |
Delivery | In Stock |
Uniprot ID | Q14626 |
IgG type | Rabbit/Human Fc chimeric IgG1 |
Clonality | Monoclonal |
Reactivity | Human |
Applications | Flow Cyt |
Recommended Dilutions | Flow Cyt 1:100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor; which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor; since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene. |
Usage | Research use only |
Conjugate | Unconjugated |
Anti-IL11RA antibody(DMC282); IgG1 Chimeric mAb
Price: 10μg $99.00 ; 100 μg $446.00 ; 500 μg $1340.00
Product Data
Images
Figure 1. IL11RA protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with Anti-IL11RA (DMC282) on Expi293 cells transfected with human IL11RA (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).
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