| Uniprot ID | P60568 |
|---|---|
| Applications | ELISA, Flow Cyt |
| Synonyms | IL-2, lymphokine, TCGF |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Description | Anti-IL2 antibody(DM187), Rabbit mAb |
| Target | |
| Recommended Dilutions | ELISA 1/5000-10000; Flow Cyt 1/100 |
| Host Species | Rabbit |
| IgG type | Rabbit IgG |
| Clonality | Monoclonal |
| Reactivity | Human |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Buffer | 1XPBS |
| Formulation & Reconstitution | Liquid |
| Delivery | In Stock |
| Usage | Research use only |
| Background | This gene is a member of the interleukin 2 (IL2) cytokine subfamily which includes IL4, IL7, IL9, IL15, IL21, erythropoietin, and thrombopoietin. The protein encoded by this gene is a secreted cytokine produced by activated CD4+ and CD8+ T lymphocytes, that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine (IL2R) is a heterotrimeric protein complex whose gamma chain is also shared by IL4 and IL7. The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. |
Anti-IL2 antibody(DM187), Rabbit mAb
Price: 10μg $99.00 ; 100 μg $438.00 ; 500 μg $1314.00
Product Data
Images
Figure 1. Flow cytometry analysis with Anti-IL2 (DM187) on Expi293 cells transfected with human IL2 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).