HAVCR2, TIM3, TIMD3, FLJ14428, KIM3
ELISA, Flow Cyt
ELISA 1/5000-10000;Flow Cyt 1/100
Purified from cell culture supernatant by affinity chromatography
|Formulation & Reconstitution||
Research use only
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
Anti-TIM3 antibody(DM81), Rabbit mAb
Price: 10μg $99.00 ; 100 μg $438.00 ; 500 μg $1314.00
Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human TIM3 protein, mFc-His tagged protein (PME100030) can bind Rabbit anti-TIM3 monoclonal antibody (clone: DM81) in a linear range of 0.32-40 ng/ml.
Figure 2. Expi 293 cell line transfected with irrelevant protein (A) and human TIM3 (B) were surface stained with Rabbit anti-TIM3 monoclonal antibody 1μg/ml (clone: DM81) followed by Alexa 488-conjugated anti-rabbit IgG secondary antibody.