| Clone ID | DM140 |
|---|---|
| Target | |
| Synonyms | TNFSF12 |
| Host Species | Rabbit |
| Description | Anti-TNFSF12 antibody(DM140); Rabbit mAb |
| Delivery | In Stock |
| Uniprot ID | O43508 |
| IgG type | Rabbit IgG |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | ELISA; Flow Cyt |
| Recommended Dilutions | ELISA 1:5000-10000; Flow Cyt 1:100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14:TWEAKR receptor. This cytokine has overlapping signaling functions with TNF; but displays a much wider tissue distribution. This cytokine; which exists in both membrane-bound and secreted forms; can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells; and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977; TNFSF12-TNFSF13. |
| Usage | Research use only |
Anti-TNFSF12 antibody(DM140); Rabbit mAb
Price: 10μg $99.00 ; 100 μg $438.00 ; 500 μg $1314.00
Product Data
Images
Figure 1. ELISA plate pre-coated by 1 μg/ml (100 μl/well) Human TNFSF12 protein, hFc tagged protein (PME100105) can bind Rabbit anti-TNFSF12 monoclonal antibody(clone: DM140) in a linear range of 5-200 ng/ml.
Figure 2. Flow cytometry analysis with Anti-TNFSF12 (DM140) on Expi293 cells transfected with human TNFSF12 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).