| Target | |
|---|---|
| Formulation & Reconstitution | Powder |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature. |
| Description | Biotinylated Anti-CD47 antibody(DM49), Rabbit mAb |
| Synonyms | CD47, MER6, IAP, OA3 |
| Uniprot ID | Q08722 |
| Applications | ELISA, Flow Cyt |
| Recommended Dilutions | ELISA 1/5000-10000; Flow Cyt 1/100 |
| Host Species | Rabbit |
| IgG type | Rabbit IgG |
| Clonality | Monoclonal |
| Reactivity | Human |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Buffer | 1XPBS |
| Delivery | 2-3 weeks |
| Usage | Research use only |
| Background | Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. |
Biotinylated Anti-CD47 antibody(DM49), Rabbit mAb
Price: 10μg $139.00 ; 100 μg $657.00 ; 500 μg $1971.00