Clone ID | DMC467 |
---|---|
Target | |
Synonyms | AAT3; FAA3; LDS1B; LDS2; LDS2B; MFS2; RIIC; TAAD2; TBR-ii; TBRII; TGFbeta-RII; TGFR-2 |
Host Species | Rabbit |
Description | Biotinylated Anti-TGFBR2 antibody(DMC467); IgG1 Chimeric mAb |
Delivery | 2-3 weeks |
Uniprot ID | P37173 |
IgG type | Rabbit/Human Fc chimeric IgG1 |
Clonality | Monoclonal |
Reactivity | Human |
Applications | Flow Cyt |
Recommended Dilutions | Flow Cyt 1:100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | The protein encoded by this gene is a transmembrane protein that has a protein kinase domain; forms a heterodimeric complex with TGF-beta receptor type-1; and binds TGF-beta. This receptor:ligand complex phosphorylates proteins; which then enter the nucleus and regulate the transcription of genes related to cell proliferation; cell cycle arrest; wound healing; immunosuppression; and tumorigenesis. Mutations in this gene have been associated with Marfan Syndrome; Loeys-Deitz Aortic Aneurysm Syndrome; and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq; Aug 2017] |
Usage | Research use only |
Biotinylated Anti-TGFBR2 antibody(DMC467); IgG1 Chimeric mAb
Price: 10μg $139.00 ; 100 μg $670.00 ; 500 μg $1999.00
Product Data
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