| Target | |
|---|---|
| Synonyms | HAVCR2, TIM3, TIMD3, FLJ14428, KIM3 |
| Host Species | Rabbit |
| IgG type | Rabbit IgG |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | ELISA, Flow Cyt |
| Recommended Dilutions | ELISA 1/5000-10000;Flow Cyt 1/100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Buffer | 1XPBS |
| Formulation & Reconstitution | Powder |
| Delivery | 2-3 weeks |
| Usage | Research use only |
| Background | The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. |
Biotinylated Anti-TIM3 antibody(DM82), Rabbit mAb
Price: 10μg $139.00 ; 100 μg $657.00 ; 500 μg $1971.00