Target | |
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Formulation & Reconstitution | Powder |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature. |
Description | Biotinylated Anti-TIM3 antibody(DM82), Rabbit mAb |
Synonyms | HAVCR2, TIM3, TIMD3, FLJ14428, KIM3 |
Uniprot ID | Q8TDQ0 |
Applications | ELISA, Flow Cyt |
Recommended Dilutions | ELISA 1/5000-10000; Flow Cyt 1/100 |
Host Species | Rabbit |
IgG type | Rabbit IgG |
Clonality | Monoclonal |
Reactivity | Human |
Purification | Purified from cell culture supernatant by affinity chromatography |
Buffer | 1XPBS |
Delivery | 2-3 weeks |
Usage | Research use only |
Background | The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. |
Biotinylated Anti-TIM3 antibody(DM82), Rabbit mAb
Price: 10μg $139.00 ; 100 μg $657.00 ; 500 μg $1971.00