ARK; UFO; AXL3; JTK11; Tyro7
Recombinant Cynomolgus AXL protein with C-terminal 10×His tag
AXL(Glu33-Pro449) 10×His tag
The protein has a predicted molecular mass of 46.5 kDa after removal of the signal peptide. The apparent molecular mass of cAXL-His is approximately 55-70 kDa due to glycosylation.
The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
|Formulation & Reconstitution||
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
|Storage & Shipping||
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized proteins are shipped at ambient temperature.
The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. The encoded protein acts as a host cell receptor for multiple viruses, including Marburg, Ebola and Lassa viruses and is a candidate receptor for the SARS-CoV2 virus. [provided by RefSeq, Sep 2021]
Research use only
Cynomolgus AXL Protein, His Tag
Price: 10μg $250.00 ; 50μg $938.00 ; 100μg $1375.00
SKU: PME-C100025 Category: ECD Proteins
Figure 1. Cynomolgus AXL Protein, His Tag on SDS-PAGE under reducing condition.