| Target | |
|---|---|
| Synonyms | P1, SI, SIL, ME20, P100, SILV, HMB45, ME20M, gp100, HMB-45, ME20-M, PMEL17, D12S53E |
| Description | Recombinant Cynomolgus PMEL protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | A0A2K5WWN0 |
| Expression Host | HEK293 |
| Tag | C-Human Fc tag |
| Molecular Characterization | Cynomolgus PMEL(Thr24-Gln602)hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 87.3 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Sterility | Products are supplied non-sterile. For cell culture applications, dilute in appropriate medium and sterile-filter (0.22 µm) prior to use. |
| Storage&Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Cynomolgus PMEL Protein, hFc Tag
Price:10μg $82.00; 50μg $320.00 ; 100 μg $480.00
Product Data Dima FAQ
Images Dima FAQ
Figure 1. Cynomolgus PMEL Protein, hFc Tag on SDS-PAGE under reducing condition.
Related Products
ECD Proteins
SKU: PME101979 Target: PMEL Tag: C-Human Fc tag
Expression Host: HEK293
Price:10μg $82.00; 50μg $320.00 ; 100 μg $480.00
Monoclonal antibodies
SKU: DMC100420P Target: PMEL
Application: Flow Cyt
Price: 100 test $550.00
Monoclonal antibodies
SKU: DMC100420 Target: PMEL
Application: Flow Cyt
Price: 100 μg $446.00 ; 500 μg $1340.00
Monoclonal antibodies
SKU: DMC100420B Target: PMEL
Application: Flow Cyt
Price: 100 μg $670.00 ; 500 μg $1999.00
ECD Proteins
SKU: PME100115 Target: PMEL Tag: C-Human Fc Tag
Expression Host: HEK293
Price: 10μg $82.00; 50μg $320.00 ; 100 μg $480.00