BCM; TNFRSF17; CD269
Recombinant human BCMA(22-42) Protein with C-terminal mouse Fc tag
C-mouse Fc tag
The protein has a predicted molecular mass of 28.5 kDa after removal of the signal peptide. The apparent molecular mass of BCMA(22-42)-mFc is approximately 25-35 kDa due to glycosylation.
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
|Formulation & Reconstitution||
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
|Storage & Shipping||
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
B-cell maturation protein (BCMA or BCM), is also known as Tumor necrosis factor receptor superfamily member 17 (TNFRSF17), which is encoded by the TNFRSF17 gene. TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). This receptor is expressed in immune organs and mature B cell lines. BCMA promotes B-cell survival and plays a role in the regulation of humoral immunity. BCMA can activate NF-kappa-B and JNK.
Research use only
Human BCMA(22-42) Protein, mFc Tag
Price: 10μg $75.00 ; 50μg $274.00 ; 100μg $411.00
SKU: PME101369 Category: ECD Proteins
Figure 1. Human BCMA(22-42) Protein, mFc Tag on SDS-PAGE under reducing condition.