| Target | |
|---|---|
| Synonyms | T-cell surface glycoprotein CD3 delta chain;T-cell receptor T3 delta chain |
| Description | Recombinant human CD3D protein with C-terminal 6×His tag |
| Delivery | In Stock |
| Uniprot ID | P04234 |
| Expression Host | HEK293 |
| Tag | C-6×His Tag |
| Molecular Characterization | CD3D(Phe22-Ala105) 6×His tag |
| Molecular Weight | The protein has a predicted molecular mass of 10.4 kDa after removal of the signal peptide. The apparent molecular mass of CD3D-His is approximately 15-25 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq, Feb 2009] |
| Usage | Research use only |
Human CD3D Protein, His Tag
Price: 10μg $85.00; 50μg $310.00 ; 100 μg $450.00
Product Data
Images
Figure 1. Human CD3D Protein, His Tag on SDS-PAGE under reducing condition.