| Synonyms | DKK-1; SK |
|---|---|
| Molecular Characterization | DKK1（Thr32-His266）+6×His tag |
| Uniprot ID | O94907 |
| Description | Recombinant Human DKK1 Protein with C-terminal 6×His tag |
| Expression Host | HEK293 |
| Molecular Weight | The protein has a predicted molecular mass of 26.6 kDa after removal of the signal peptide. The apparent molecular mass of DKK1-His is approximately 35-55 kDa due to glycosylation. |
| Delivery | In Stock |
| Purity | The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized proteins are shipped at ambient temperature. |
| Package | 10μg $71.00 ; 50μg $259.00 ; 100μg $389.00 |
| Usage | Research use only |
| Background | This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote proliferation, invasion and growth in cancer cell lines. [provided by RefSeq, Sep 2017] |
Human DKK1 Protein, His Tag
Price: 10μg $71.00 ; 50μg $259.00 ; 100μg $389.00
Product Data
Images
Figure 1.Human DKK1 Protein, His Tag on SDS-PAGE under reducing condition.