| Tag | C-Flag Tag | 
|---|---|
| Target | |
| Synonyms | DADR, DRD1A | 
| Description | Human DRD1 full length protein-synthetic nanodisc | 
| Delivery | 6~8weeks | 
| Uniprot ID | P21728 | 
| Expression Host | HEK293 | 
| Protein Families | GPCR,Transmembrane,Druggable Genome, | 
| Protein Pathways | GPCRDB Class A Rhodopsin-like,Monoamine GPCRs,G-Protein Coupled Receptors Signaling Pathway, | 
| Molecular Weight | The human full length DRD1 protein has a MW of 49.3kDa | 
| Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. | 
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. | 
| Background | This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008] | 
| Usage | Research use only | 
| Conjugate | Unconjugated | 

Human DRD1 full length protein-synthetic nanodisc
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