| Target | |
|---|---|
| Synonyms | FXI; PTA |
| Description | Recombinant human F11 Protein with C-terminal 3×Flag tag |
| Delivery | In Stock |
| Uniprot ID | P03951 |
| Expression Host | HEK293 |
| Tag | C-3×Flag Tag |
| Molecular Characterization | F11(Met1-Val625) 3×Flag tag |
| Molecular Weight | The protein has a predicted molecular mass of 73.1 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq, Jul 2008] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human F11 Protein, Flag Tag
Price:10μg $100.00 ; 50μg $358.00 ; 100μg $528.00
Product Data Dima FAQ
Images Dima FAQ
Figure 1. Human F11 Protein, Flag Tag on SDS-PAGE under reducing condition.
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