Tag | C-Flag Tag |
---|---|
Target | |
Synonyms | Frizzled-1; Fz-1; hFz1; FzE1 |
Description | Human FZD1 full length protein-synthetic nanodisc |
Delivery | 6~8weeks |
Uniprot ID | Q9UP38 |
Expression Host | HEK293 |
Protein Families | GPCR,Transmembrane,Druggable Genome, |
Protein Pathways | Adipogenesis,Wnt NetPath 8,Wnt signaling,Wnt signaling and pluripotency,Cancer,Notch,Wnt Pathway,Stem Cell , |
Molecular Weight | The human full length FZD1 protein has a MW of 71.2kDa |
Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with pH lower than 6.5 in subsequent experiments. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues. [provided by RefSeq, Jul 2008] |
Usage | Research use only |
Human FZD1 full length protein-synthetic nanodisc
Price: 10 μg $900.00 ; 50 μg $4400.00 ; 100 μg $8000.00
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