| Tag | C-Flag Tag |
|---|---|
| Target | |
| Synonyms | N/A |
| Description | Human GBRA4 full length protein-synthetic nanodisc |
| Delivery | 6~8weeks |
| Uniprot ID | P48169 |
| Expression Host | HEK293 |
| Protein Families | Ion Channels: Cys-loop Receptors |
| Protein Pathways | N/A |
| Molecular Weight | The human full length GBRA4 protein has a MW of 61.6kDa |
| Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.[provided by RefSeq, Feb 2011] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human GBRA4 full length protein-synthetic nanodisc
Product Data Dima FAQ
Images Dima FAQ
Related Products
Full Length Transmembrane Proteins
SKU: FLP120803 Target: GBRA4
Price: 10 μg $810.00 ; 50 μg $3960.00 ; 100 μg $7200.00