| Target | |
|---|---|
| Synonyms | GPR15, BOB, G protein-coupled receptor 15, HPT-3-2 |
| Description | Recombinant human GPR15 Protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | P49685 |
| Expression Host | HEK293 |
| Tag | C-Human Fc tag |
| Molecular Characterization | GPR15(Met1-Ser33) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 30.0 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | GPR15 (G protein-coupled receptor 15 / BOB) is a G-protein coupled receptor (GPCR) expressed in T cells, colon, and vascular endothelium. It primarily couples to Gi/o proteins, modulating cAMP levels and intracellular signaling pathways. GPR15 functions as a lymphocyte homing receptor, directing T cell migration to the colon and mucosal tissues, and is implicated in immune regulation, inflammation, and HIV/SIV entry. Dysregulation of GPR15 is associated with autoimmune and inflammatory diseases, making it a potential therapeutic target in immunology. |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human GPR15 Protein, hFc Tag
Price:10μg $95.00 ; 50μg $330.00 ; 100μg $500.00
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Figure 1. Human GPR15 Protein, hFc Tag on SDS-PAGE under reducing condition.
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