BB2; BB2R; BRS2
Recombinant Human GRPR Protein with C-terminal human Fc tag
The protein has a predicted molecular mass of 30.4 kDa after removal of the signal peptide. The apparent molecular mass of GRPR-hFc is approximately 35-55 kDa due to glycosylation.
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
|Formulation & Reconstitution||
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
|Storage & Shipping||
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized proteins are shipped at ambient temperature.
10μg $67.00 ; 50μg $244.00 ; 100μg $367.00
Research use only
Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. [provided by RefSeq, Jul 2008]
Human GRPR Protein, hFc Tag
Price: 10μg $67.00 ; 50μg $244.00 ; 100μg $367.00
SKU: PME101268 Category: ECD Proteins
Figure 1.Human GRPR Protein, hFc Tag on SDS-PAGE under reducing condition.