| Target | |
|---|---|
| Synonyms | Interleukin-20 receptor subunit beta;IL-20 receptor subunit beta;IL-20R-beta;IL-20RB;IL-20R2;DIRS1;hCG_2022374;FNDC6;MGC34923;fibronectin type III domain containing 6;interleukin-20 receptor II |
| Description | Recombinant Human Interleukin-20 Receptor Subunit Beta/IL-20RB is produced by our Mammalian expression system and the target gene encoding Asp30-Ala230 is expressed with a Fc tag at the C-terminus. |
| Delivery | In Stock |
| Uniprot ID | Q6UXL0 |
| Expression Host | HEK293 |
| Tag | C-Fc Tag |
| Molecular Characterization | Not available |
| Molecular Weight | 49.6 KDa |
| Purity | Greater than 85% as determined by reducing SDS-PAGE. |
| Formulation & Reconstitution | Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| Storage & Shipping | Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| Background | Interleukin-20 receptor subunit beta(IL20RB) is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family. |
| Usage | Research use only |
Human IL-20RB (C-Fc) Protein
Price: 50 μg $286.00
Product Data
Images
Figure 1. Greater than 95% as determined by reducing SDS-PAGE.