| Target | |
|---|---|
| Synonyms | Interleukin-28B;IL-28B;Cytokine Zcyto22;Interferon Lambda-3;IFN-Lambda-3;Interferon Lambda-4;IFN-Lambda-4;Interleukin-28C;IL-28C;IL28B;IFNL3;IFNL4;IL28C;ZCYTO22 |
| Description | Recombinant Human Interleukin-28B is produced by our Mammalian expression system and the target gene encoding Val22-Val196 is expressed. |
| Delivery | In Stock |
| Uniprot ID | Q8IZI9 |
| Expression Host | HEK293 |
| Tag | |
| Molecular Characterization | Not available |
| Molecular Weight | 19.6 KDa |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Formulation & Reconstitution | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM EDTA, pH 7.4. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Interleukin-28B, also known as Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, IFNL3, IFNL4, ZCYTO22 and IL28B, is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition, IL28B is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway. |
| Usage | Research use only |
Human IL-28B Protein
Price: 50 μg $360.00
Product Data
Images
Figure 1. Greater than 95% as determined by reducing SDS-PAGE.